Controlling persistent organic pollutants–what next?
Identifieur interne : 000E87 ( Main/Exploration ); précédent : 000E86; suivant : 000E88Controlling persistent organic pollutants–what next?
Auteurs : Harry W. Vallack [Royaume-Uni] ; Dick J. Bakker [Pays-Bas] ; Ingvar Brandt [Suède] ; Eva Broström-Lundén [Suède] ; Abraham Brouwer [Pays-Bas] ; Keith R. Bull [Royaume-Uni] ; Clair Gough [Italie] ; Ramon Guardans [Espagne] ; Ivan Holoubek [République tchèque] ; Bo Jansson [Suède] ; Rainer Koch [Allemagne] ; Johan Kuylenstierna [Royaume-Uni] ; André Lecloux [Belgique] ; Donald Mackay [Canada] ; Patrick Mccutcheon [Belgique] ; Paolo Mocarelli [Italie] ; Rob D. F. Taalman [Belgique]Source :
- Environmental Toxicology and Pharmacology [ 1382-6689 ] ; 1998.
English descriptors
- KwdEn :
Abstract
Within the context of current international initiatives on the control of persistent organic pollutants (POPs), an overview is given of the scientific knowledge relating to POP sources, emissions, transport, fate and effects. At the regional scale, improvements in mass balance models for well-characterised POPs are resulting in an ability to estimate their environmental concentrations with sufficient accuracy to be of help for some regulatory purposes. The relevance of the parameters used to define POPs within these international initiatives is considered with an emphasis on mechanisms for adding new substances to the initial lists. A tiered approach is proposed for screening the large number of untested chemical substances according to their long-range transport potential, persistence and bioaccumulative potential prior to more detailed risk assessments. The importance of testing candidate POPs for chronic toxicity (i.e. for immunotoxicity, endocrine disruption and carcinogenicity) is emphasised as is a need for the further development of relevant SAR (structure activity relationship) models and in vitro and in vivo tests for these effects. Where there is a high level of uncertainty at the risk assessment stage, decision-makers may have to rely on expert judgement and weight-of-evidence, taking into account the precautionary principle and the views of relevant stake-holders. Close co-operation between the various international initiatives on POPs will be required to ensure that assessment criteria and procedures are as compatible as possible.
Url:
DOI: 10.1016/S1382-6689(98)00036-2
Affiliations:
- Allemagne, Belgique, Canada, Espagne, Italie, Pays-Bas, Royaume-Uni, République tchèque, Suède
- Communauté de Madrid, Moravie, Région de Bruxelles-Capitale, Svealand
- Brno, Bruxelles, Madrid, Stockholm
- Université de Stockholm
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F." last="Taalman">Rob D. F. Taalman</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>European Chemical Industry Council (CEFIC)–Endocrine Modulators Steering Group (EMSG), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Environmental Toxicology and Pharmacology</title><title level="j" type="abbrev">ENVTOX</title><idno type="ISSN">1382-6689</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1998">1998</date><biblScope unit="volume">6</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="143">143</biblScope><biblScope unit="page" to="175">175</biblScope></imprint><idno type="ISSN">1382-6689</idno></series><idno type="istex">509CD769B4D172D70ABEC56F522E99C6BB415618</idno><idno type="DOI">10.1016/S1382-6689(98)00036-2</idno><idno type="PII">S1382-6689(98)00036-2</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1382-6689</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bioaccumulation</term><term>Biomagnification</term><term>Carcinogenicity</term><term>Chronic toxicity</term><term>Endocrine disruption</term><term>Global distillation</term><term>Immunotoxicity</term><term>Monitoring</term><term>Persistence</term><term>Persistent organic pollutants</term><term>Risk assessment</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Within the context of current international initiatives on the control of persistent organic pollutants (POPs), an overview is given of the scientific knowledge relating to POP sources, emissions, transport, fate and effects. At the regional scale, improvements in mass balance models for well-characterised POPs are resulting in an ability to estimate their environmental concentrations with sufficient accuracy to be of help for some regulatory purposes. The relevance of the parameters used to define POPs within these international initiatives is considered with an emphasis on mechanisms for adding new substances to the initial lists. A tiered approach is proposed for screening the large number of untested chemical substances according to their long-range transport potential, persistence and bioaccumulative potential prior to more detailed risk assessments. The importance of testing candidate POPs for chronic toxicity (i.e. for immunotoxicity, endocrine disruption and carcinogenicity) is emphasised as is a need for the further development of relevant SAR (structure activity relationship) models and in vitro and in vivo tests for these effects. Where there is a high level of uncertainty at the risk assessment stage, decision-makers may have to rely on expert judgement and weight-of-evidence, taking into account the precautionary principle and the views of relevant stake-holders. Close co-operation between the various international initiatives on POPs will be required to ensure that assessment criteria and procedures are as compatible as possible.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Belgique</li><li>Canada</li><li>Espagne</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>République tchèque</li><li>Suède</li></country><region><li>Communauté de Madrid</li><li>Moravie</li><li>Région de Bruxelles-Capitale</li><li>Svealand</li></region><settlement><li>Brno</li><li>Bruxelles</li><li>Madrid</li><li>Stockholm</li></settlement><orgName><li>Université de Stockholm</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Vallack, Harry W" sort="Vallack, Harry W" uniqKey="Vallack H" first="Harry W." last="Vallack">Harry W. Vallack</name></noRegion><name sortKey="Bull, Keith R" sort="Bull, Keith R" uniqKey="Bull K" first="Keith R." last="Bull">Keith R. Bull</name><name sortKey="Kuylenstierna, Johan" sort="Kuylenstierna, Johan" uniqKey="Kuylenstierna J" first="Johan" last="Kuylenstierna">Johan Kuylenstierna</name></country><country name="Pays-Bas"><noRegion><name sortKey="Bakker, Dick J" sort="Bakker, Dick J" uniqKey="Bakker D" first="Dick J." last="Bakker">Dick J. Bakker</name></noRegion><name sortKey="Brouwer, Abraham" sort="Brouwer, Abraham" uniqKey="Brouwer A" first="Abraham" last="Brouwer">Abraham Brouwer</name></country><country name="Suède"><noRegion><name sortKey="Brandt, Ingvar" sort="Brandt, Ingvar" uniqKey="Brandt I" first="Ingvar" last="Brandt">Ingvar Brandt</name></noRegion><name sortKey="Brostrom Lunden, Eva" sort="Brostrom Lunden, Eva" uniqKey="Brostrom Lunden E" first="Eva" last="Broström-Lundén">Eva Broström-Lundén</name><name sortKey="Jansson, Bo" sort="Jansson, Bo" uniqKey="Jansson B" first="Bo" last="Jansson">Bo Jansson</name></country><country name="Italie"><noRegion><name sortKey="Gough, Clair" sort="Gough, Clair" uniqKey="Gough C" first="Clair" last="Gough">Clair Gough</name></noRegion><name sortKey="Mocarelli, Paolo" sort="Mocarelli, Paolo" uniqKey="Mocarelli P" first="Paolo" last="Mocarelli">Paolo Mocarelli</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Guardans, Ramon" sort="Guardans, Ramon" uniqKey="Guardans R" first="Ramon" last="Guardans">Ramon Guardans</name></region></country><country name="République tchèque"><region name="Moravie"><name sortKey="Holoubek, Ivan" sort="Holoubek, Ivan" uniqKey="Holoubek I" first="Ivan" last="Holoubek">Ivan Holoubek</name></region></country><country name="Allemagne"><noRegion><name sortKey="Koch, Rainer" sort="Koch, Rainer" uniqKey="Koch R" first="Rainer" last="Koch">Rainer Koch</name></noRegion></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Lecloux, Andre" sort="Lecloux, Andre" uniqKey="Lecloux A" first="André" last="Lecloux">André Lecloux</name></region><name sortKey="Mccutcheon, Patrick" sort="Mccutcheon, Patrick" uniqKey="Mccutcheon P" first="Patrick" last="Mccutcheon">Patrick Mccutcheon</name><name sortKey="Taalman, Rob D F" sort="Taalman, Rob D F" uniqKey="Taalman R" first="Rob D. F." last="Taalman">Rob D. F. Taalman</name></country><country name="Canada"><noRegion><name sortKey="Mackay, Donald" sort="Mackay, Donald" uniqKey="Mackay D" first="Donald" last="Mackay">Donald Mackay</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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